Hepatotoxic Assessment of Phyllanthus amarus leaf Extract in Wistar Rats
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چکیده
منابع مشابه
Evaluation of Antifertility Effects of Aqueous Extract of Phyllanthus Amarus in Male Wistar Rats
The present study was aimed at evaluating the antifertility effect of phyllanthus amarus extract in male wistar rats. The body and organ weights, cauda epididymal sperm parameters, serum levels of male reproductive hormones and fructose were assessed. Daily oral doses of the extract were administered to each animal in three different test groups for 28 consecutive days. Results show significant...
متن کاملAnalgesic activity of aqueous leaf extract of Phyllanthus amarus.
Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and chemical models of pain assessment in rats. The extract caused a significant (P < 0.05) dose related increase inhibition of the carrageenan-induced paw oedema in the rats. The inhibition produced by 200 mg/kg AEPA (70.20%) was significantly hi...
متن کاملEffects of oral administration of Phyllanthus amarus leaf extract on the kidneys of adult wistar rats: a histological study.
Histological studies of the effects of oral administration of aqueous extract of Phyllanthus amarus commonly used in ethno medical practice in Africa for the management of various ailments such as kidney stones, dysentery, jaundice, diarrhoea and urogenital diseases on the kidney of adult Wistar rats were carefully studied. Rats of both sexes (n=24), average weight of 260g were randomly assigne...
متن کاملImmunosuppressive effects of the standardized extract of Phyllanthus amarus on cellular immune responses in Wistar-Kyoto rats
Phyllanthus amarus (family: Euphorbiaceae) is of immense interest due to its wide spectrum of biological activities. In the present study, the standardized 80% ethanol extract of P. amarus was investigated for its modulatory activity on various cellular immune parameters, including chemotaxis of neutrophils, engulfment of Escherichia coli by neutrophils, and Mac-1 expression, in leukocytes isol...
متن کاملEFFECT OF ETHANOLIC EXTRACT OF PHYLLANTHUS AMARUS AND TYLOPHORA INDICA ON ISONIAZID INDUCED HEPATIC INJURY IN WISTAR ALBINO RATS. Shyamjith
Objective: To assess the hepatoprotective effect of ethanolic extract of leaves and stem of Phyllanthus amarus and ethanolic extract of leaves of Tylophora indica against Isoniazid induced liver toxicity in experimental animals. Methods: Liver toxicity was induced by administering Isoniazid 27mg/kg orally for 30 days in Wistar albino rats. Ethanolic (90%) extracts of Phyllanthus amarus (PAEE) a...
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ژورنال
عنوان ژورنال: European Journal of Medicinal Plants
سال: 2018
ISSN: 2231-0894
DOI: 10.9734/ejmp/2018/41238